Table 3.
Assessment of Anticoagulation parameters among Pre-VAC (pre COVID) and VAC care.
| Anticoagulation parameters | VAC care (n = 228) | Pre-COVID care (n = 228) | p-value | ACC COVID-19 care (n = 274) | ACC pre-COVID care (n = 274) | p-value |
|---|---|---|---|---|---|---|
| Number of INR† draws | 1,324 | 1,467 | 1,019 | 1,551 | ||
| Average number of INR† draws/ Patient | 5.8 | 6.43 | - | 3.72 | 5.66 | - |
| Mean TTR%* | 75.4 ± 8.91 | 77.58 ± 8.85 | 0.0506# | 71.2 ± 13.4 | 79.12 ± 9.3 | <0.0001# |
| Mean PINRR %** | 66.7 ± 9.4 % | 69.68 ± 11.50 | 0.0241# | 62.4 ± 10.9% | 67.8 ± 10.4 | <0.0001# |
| Tests Over Range | 129 (9.7) | 118 (8.1) | 0.1375 | 113 (11.11) | 96 (6.2) | <0.0001†† |
| Tests Below range | 151 (11.7) | 106 (7.26) | 0.0001†† | 142 (13.9) | 129 (8.3) | <0.0001†† |
| Extreme INRs | ||||||
| INR >5.0 | 14 (1.06) | 0 | - | 15 (1.51) | 10 (0.66) | 0.0339†† |
| INR <1.5 | 30 (2.26) | 11 (0.75) | 0.0009†† | 75 (7.32) | 8 (0.5) | <0.0001†† |
| Adverse events | ||||||
| Major | 0 (0%) | 0 | - | 0 | 0 | - |
| Minor bleeding | 2 (0.8%) | 0 | 0 | 0 | ||
†
INR: International Normalized Ratio;
**
PINRR: Percentage of International Normalized Ratio in the Therapeutic Range
*
TTR: Time in Therapeutic Range.
††
statistically significant p-value has been obtained by performing chi-squared test.
#
statistically significant p-value has been obtained by performing t-test.