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. 2021 Mar 29;11:642903. doi: 10.3389/fcimb.2021.642903

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Copyright © 2021 Zhao, Song, An, Dong, Li, Wang, Liu, Tian, Wang, Ding, Han and Shang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Phylogenetic analysis of subtype CRF07_BC. The phylogenetic tree was constructed using the maximum-likelihood method based on the pol region (HXB2: 2,253 to 3,300nt). HIV-1 subtype CRF01_AE was chosen as an out-group in the CRF07_BC rooted tree. Only the sequences within the two lineages of CRF07_BC (88.8%, 349/393) were included in this ML tree. The molecular cluster (pink) including the strains with K103N (green) located in the main lineage of CRF07_BC (red).