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Effect of veverimer on serum bicarbonate concentration in individuals with metabolic acidosis and chronic kidney disease. At week 52, mean serum bicarbonate level was 2.0 (SD, 0.5) mEq/L higher than in the placebo group. Serum bicarbonate levels decreased after stopping active treatment. Adapted from Wesson et al13 with permission from the copyright holder (Elsevier).
