Table 3.

Main Effect and Interaction Estimates From Longitudinal Linear Mixed Models Associating Anterior Lamina Cribrosa Surface Depth With (A) Each Variable of Interest and Time Included as Independent Variables and (B) Each Variable of Interest, Time, and Their Interaction Included as Independent Variables

	Longitudinal ALCSD, Univariable Models
	(A) Main Effect	P Value	(B) Time Interaction	P Value
Age	−2.76 (−4.73 to −0.78)	0.007	−0.01 (−0.12 to 0.10)	0.842
Gender: M	59.92 (15.45 to 104.40)	0.009	−0.13 (−2.53 to 2.26)	0.913
Race: European descent	−83.74 (−127.37 to −40.11)	<0.001	2.55 (0.18 to 4.93)	0.037
VFbase	0.12 (−0.23 to 0.48)	0.503	−0.04 (−0.18 to 0.11)	0.632
SE	−0.37 (−12.91 to 12.17)	0.954	0.37 (−0.28 to 1.03)	0.264
AL	12.72 (−8.82 to 34.26)	0.249	−0.30 (−1.45 to 0.86)	0.615
Disc area	63.96 (18.72 to 109.20)	0.006	−0.83 (−3.37 to 1.71)	0.523
IOP	0.01 (−0.28 to 0.30)	0.955	0.06 (−0.16 to 0.29)	0.579
Maximum IOP	7.00 (1.78 to 12.23)	0.009	−0.05 (−0.33 to 0.23)	0.715
CCT	0.12 (−0.44 to 0.67)	0.685	0.01 (−0.02 to 0.04)	0.538

VFbase, visual field mean deviation at baseline; SE, spherical equivalent; AL, axial length; IOP, intraocular pressure; IOPbase, intraocular pressure at baseline; CCT, central corneal thickness.

Bold P values are significant.