| 0a |
Ta |
Non-invasive papillary carcinoma (Ta) with no nodal involvement (N0) or distant sites (M0) |
| N0 |
| M0 |
| 0is |
Tis |
Flat, non-invasive carcinoma (Tis)—also known as flat carcinoma in situ (CIS), with no nodal involvement (N0) or distant sites (M0) |
| N0 |
| M0 |
| I |
T1 |
The cancer has grown into the layer of connective tissue under the lining layer of the bladder, without reaching the layer of muscle in the bladder wall (T1). No nodal involvement (N0) or distant sites (M0) |
| N0 |
| M0 |
| II |
T2a or T2b |
The cancer involves the inner (T2a) or the outer (T2b) muscle layer of the bladder wall, without completely passing through the muscle to reach the layer of fatty tissue surrounding the bladder. No nodal involvement (N0) or distant sites (M0) |
| N0 |
| M0 |
| IIIA |
T3a, T3b or T4a |
The cancer involves the muscle layer of the bladder, reaching the layer of fatty tissue surrounding the bladder (T3a or T3b). No nodal involvement (N0) or distant sites (M0) |
| N0 |
| M0 |
| OR |
| T1-T4a |
The cancer is not growing into the pelvic or abdominal wall (T1-T4a) and it has spread to 1 nearby lymph node in the true pelvis (N1). No distant sites (M0) |
| N1 |
| M0 |
| IIIB |
T1-T4a |
The cancer is not growing into the pelvic or abdominal wall (T1-T4a) and it has spread to 2 or more lymph nodes in the true pelvis (N2) or to lymph nodes along the common iliac arteries (N3). No distant sites (M0) |
| N2 or N3 |
| M0 |
| IVA |
T4b |
The cancer has grown through the bladder wall into the pelvic or abdominal wall (T4b). It might have spread to nearby lymph nodes or not (Any N). No distant sites (M0) |
| Any N |
| M0 |
| OR |
| Any T |
The cancer has spread to distant lymph nodes (M1a) |
| Any N |
| M1a |
| IVB |
Any T |
The cancer has spread to 1 or more distant organs (M1b) |
| Any N |
| M1b |
