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. 2021 Mar;10(3):1229–1240. doi: 10.21037/tau-20-1353

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2021 Translational Andrology and Urology. All rights reserved.

Open Access Statement: This is an Open Access article distributed in accordance with the Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International License (CC BY-NC-ND 4.0), which permits the non-commercial replication and distribution of the article with the strict proviso that no changes or edits are made and the original work is properly cited (including links to both the formal publication through the relevant DOI and the license). See: https://creativecommons.org/licenses/by-nc-nd/4.0.

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Construction of a prognostic immune-related gene signature using powerful biomarkers. (A) Cluster tree of bladder cancer samples in TCGA. The colour bar below the cluster tree shows the numerical number of clinical characteristics; (B) different IRG modules displayed in the Cluster dendrogram; (C) correlations between gene modules and clinical characteristics displayed in the heatmap; (D) Scatter diagram of module membership versus gene significance for OS in the yellow module; (E) the results of univariate Cox regression analysis shown in the volcano plot; (F) the risk scores for bladder cancer patients as calculated by the LASSO Cox regression model; (G) coefficients of the six immune-related genes.