Table 5. Treatment-related adverse events occurring in at least 10% of patients (n=32).
| Adverse events | No. grade 1/2 [%] | No. grade 3 [%] | Total No. [%] |
|---|---|---|---|
| Changes in hair color | 22 [69] | 0 [0] | 22 [69] |
| Diarrhea | 15 [47] | 5 [16] | 20 [63] |
| Hypertension | 11 [34] | 5 [16] | 16 [50] |
| Fatigue | 14 [44] | 1 [3] | 15 [47] |
| Nausea | 13 [41] | 0 [0] | 13 [41] |
| Hand-foot syndrome | 7 [22] | 5 [16] | 12 [38] |
| Stomatitis | 12 [38] | 0 [0] | 12 [38] |
| Increased ALT | 7 [22] | 4 [12] | 11 [34] |
| Increased AST | 7 [22] | 3 [9] | 10 [31] |
| Alopecia | 9 [28] | 0 [0] | 9 [28] |
| Vomit | 8 [25] | 1 [3] | 9 [28] |
| Abdominal pain | 8 [25] | 0 [0] | 8 [25] |
| Neutrocytopenia | 5 [16] | 2 [6] | 7 [22] |
| Rash | 5 [16] | 1 [3] | 6 [19] |
| Proteinuria | 3 [10] | 3 [10] | 6 [19] |
| hypothyroidism | 5 [16] | 0 [0] | 5 [16] |
| Hemoglobin decreased | 4 [13] | 0 [0] | 4 [13] |
ALT, alanine aminotransferase; AST, aspartate aminotransferase.