Table 2. Clinical data of patients with malignant SPNs.
| Clinical data | Case number (n=184) | CTCs level (FU/3 mL) | F/χ2 | P |
|---|---|---|---|---|
| Age (years) | ||||
| ≤60 | 94 | 9.55±2.74 | 4.671 | <0.001 |
| >60 | 90 | 11.45±3.92 | ||
| Sex | ||||
| Male | 79 | 10.45±3.94 | 0.984 | 0.923 |
| Female | 105 | 10.50±3.13 | ||
| Pathological subtypes | ||||
| Squamous cell carcinoma | 34 | 9.10±1.94 | 3.436 | 0.034 |
| Adenocarcinoma | 147 | 10.77±3.71 | ||
| Adenosquamous cell carcinoma | 3 | 11.78±2.61 | ||
| Differentiation grade | ||||
| G1 | 99 | 10.39±3.74 | 0.899 | 0.409 |
| G2 | 57 | 10.25±3.37 | ||
| G3 | 18 | 11.29±2.75 | ||
| Location of SPN | ||||
| Left lobe | 91 | 10.49±4.02 | 3.731 | 0.968 |
| Right lobe | 93 | 10.47±2.91 | ||
| Location of SPN | ||||
| Upper lobe | 121 | 10.51±3.38 | 0.943 | 0.391 |
| Middle lobe | 8 | 8.85±1.84 | ||
| Lower lobe | 55 | 10.65±3.89 | ||
| Largest diameter of SPN (cm) | ||||
| ≤1 | 66 | 10.22±3.53 | 0.512 | 0.475 |
| >1 | 118 | 10.63±3.48 | ||
| T staging | ||||
| T1 | 126 | 10.57±3.71 | 0.964 | 0.383 |
| T2 | 42 | 9.92±3.11 | ||
| T3 | 16 | 11.25±2.43 | ||
| N staging | ||||
| N0 | 153 | 10.44±3.40 | 0.344 | 0.709 |
| N1 | 25 | 10.43±4.11 | ||
| N2 | 6 | 11.65±3.38 | ||
| TNM staging | ||||
| Stage I | 137 | 10.35±3.50 | 0.553 | 0.576 |
| Stage II | 41 | 10.75±3.53 | ||
| Stage III | 6 | 11.65±3.38 | ||
| Smoking history | ||||
| N/A | 160 | 10.43±3.25 | 1.914 | 0.168 |
| I/A | 24 | 10.82±4.89 |
SPN, solitary pulmonary nodule; CTC, circulating tumor cell; N/A, not available; I/A, is available.