Table 3. Logistic regression analysis of independent risk factors for malignant SPNs.
| Variables | B | SE | Wald | P | OR | 95% CI |
|---|---|---|---|---|---|---|
| CTCs | 1.318 | 0.702 | 4.817 | 0.030 | 3.698 | 1.136–11.035 |
| CEA | 0.518 | 0.626 | 0.725 | 0.415 | 1.661 | 0.526–5.336 |
| CA125 | 0.221 | 0.359 | 0.624 | 0.234 | 1.567 | 0.367–4.267 |
| CA724 | 0.456 | 0.547 | 0.636 | 0.365 | 1.778 | 0.412–3.612 |
| CYFRA21-1 | 0.697 | 0.627 | 0.784 | 0.657 | 3.364 | 0.524–6.147 |
| NSE | 0.239 | 0.412 | 0.125 | 0.362 | 2.263 | 0.127–5.236 |
SPN, solitary pulmonary nodule; CTC, circulating tumor cell; CEA, carcinoembryonic antigen; CA125, carbohydrate antigen 125; CA724, carbohydrate antigen 724; CYFRA21-1, cytokeratin fragment 21-1; NSE, neuron-specific enolase.