Effect of JP4-039 on sulfite-induced alterations on heme oxygenase-1 (HO-1), A, catalase (CAT), B, and superoxide dismutase 1 (SOD1), C, content in rat striatum 30 minutes after sulfite injection (2 μmol). Pretreatment with JP4-039 was performed via intraperitoneal injection 24 (5.0 μg/g) and 2 hours (5.0 μg/g) prior to sulfite administration. Values are means ± SD for three to four independent experiments (animals) per group. **P < .01, ***P < .001, compared to rats receiving NaCl (2 μmol) (control group); #P < .05, ##P < .01, ###P < .001, compared to rats receiving sulfite (sulfite group) (Duncan multiple range test)