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. Author manuscript; available in PMC: 2021 Apr 12.
Published in final edited form as: Inhal Toxicol. 2020 Feb 26;32(1):1–13. doi: 10.1080/08958378.2020.1725187

Table 6.

Significant effects on the other systems resulting from exposure to particle filtered diesel exhaust (fDE) or whole diesel exhaust (wDE) relative to filtered air exposure (arrows indicate direction of effect and statistical significance at α < 0.05; dashes indicate no statistically significant effect observed). NR = not reported.

Other
PM μg/m3 NO2 (ppm) Species Sex Duration Effect fDE wDE Author Year
fDE wDE fDE wDE
<1 2300 NR NR Wistar rat Male 3 hr/day, 5 day/week for 3 weeks γH2AX - Douki et al. 2018
Fold change in lung tissue gene expression of cell cycle and DNA repair pathways -
0.69 41.7 (low), 152 (high) 0.53 0.16 (low), 0.54 (high) C57BL/Jcl mice Male 5 hr/day, 5 days/week for 8 weeks Adrenocorticotropic hormone -stimulated hormone release from adrenal cells Li et al. 2012b
3.1 148.86 0.51 0.53 Fischer rats Male (in utero exposure) 5 hr/day during days 1–19 of gestation Corticosterone Li et al. 2009