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. 2021 Mar 13;11(11):5464–5490. doi: 10.7150/thno.54822

Table 3.

Characterization of silica nanoparticles

Investigators Nanoparticles
(NPs)
Average particle size (nm)(±S.D.) Zeta potential
(mV)(±S.D.)
Entrapment efficiency (EE%) Drug loading
(DL%)
Drug release
%
PDI
Zhao et al. 37 SO@MSN-CS-LA 210.9 (±2.8) +7.7 (±2.6) 57.4(±2.1) 21.3(±0.9) 24.9(pH=7.4)
65.0(pH=5.5)
0.258 (±0.022)
Ye et al. 131 LDL-SLN/Sor/Dox 110.9(±6.8) -18.3(±4.1) -- 37.1 <15(pH=7.4)
47.6(pH=5.5)
0.118
Zheng et al. 138 SO/siVEGF@MSN-LA 148.5 (±3.5) + 8.3(±3.5) 55.3(±2.9) 21.8(±1.6) ≈30(pH=7.4)
≈60(pH=5.5)
0.153(±0.072)
Tang et al. 195 MMSNs@SO
5(TEOS): 1(MnCl2)
102.6(±3.06) -25.43 5.36(±0.64) 2.68(±0.32) 5.02±1.05(pH=7.4)
23.13±1.45(pH=5.0)
0.119(±0.01)
Yang et al. 174 (ICG+S)@mSiO2
ICG(1):S(3)
≈100 ≈-17 -- 9.75 18.8(pH=7.4)
22.36(pH=5.5)
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