Table 3.

Summary of methods for identifying personalised cancer drivers

Method	Description and reference	Additional information
Personalised cancer driver identification
DawnRank	A ranking framework which applies PageRank to evaluate the impact of genes in an interaction network to detect cancer drivers 51	It bases on the same gene network for all patients, thus may reduce the personalised information
SCS	Detects the minimal set of mutated genes controlling the maximal differentially expressed genes as cancer drivers 52	It builds a gene network for each patient; its application is limited as it requires the corresponding normal sample for each patient
PNC	Identifies cancer drivers as the minimum gene set which covers all the edges based on a bipartite graph 53	It also requires the corresponding normal sample for each patient