Table 6.
KEGG pathways involved in breast cancer in which the predicted cancer drivers are enriched
| Term | #Genes | p-value |
|---|---|---|
| ErbB signaling pathway | 6 | 5.3e-06 |
| Thyroid hormone signaling pathway | 6 | 2.8e-05 |
| Sphingolipid signaling pathway | 6 | 3.1e-05 |
| Neurotrophin signaling pathway | 6 | 3.0e-05 |
| PI3K-Akt signaling pathway | 8 | 1.7e-04 |
| AGE-RAGE signaling pathway in diabetic complications | 5 | 1.7e-04 |
| HIF-1 signaling pathway | 5 | 1.7e-04 |
| FoxO signaling pathway | 5 | 5.1e-04 |
| Fc epsilon RI signaling pathway | 4 | 5.2e-04 |
| Toll-like receptor signaling pathway | 4 | 2.2e-03 |
| TNF signaling pathway | 4 | 2.7e-03 |
| Relaxin signaling pathway | 4 | 4.6e-03 |
| VEGF signaling pathway | 3 | 5.1e-03 |
| Estrogen signaling pathway | 4 | 5.3e-03 |
| mTOR signaling pathway | 4 | 7.3e-03 |
| Prolactin signaling pathway | 3 | 7.4e-03 |
| B cell receptor signaling pathway | 3 | 7.6e-03 |
| p53 signaling pathway | 3 | 7.8e-03 |
| MAPK signaling pathway | 5 | 1.2e-02 |
| T cell receptor signaling pathway | 3 | 1.8e-02 |
| Rap1 signaling pathway | 4 | 1.8e-02 |
| C-type lectin receptor signaling pathway | 3 | 1.9e-02 |
| AMPK signaling pathway | 3 | 2.6e-02 |
| Apelin signaling pathway | 3 | 3.5e-02 |
| Insulin signaling pathway | 3 | 3.4e-02 |
| Phospholipase D signaling pathway | 3 | 4.1e-02 |