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. 2021 Mar 12;11(11):5387–5403. doi: 10.7150/thno.42345

Figure 5.

Figure 5

LCN2 is a functional mediator of PRMT1 in ccRCC cells. (A-B) SRB assays were performed to evaluate the proliferation of LCN2-deleted A498 and Caki-1 cells. (C) Colony formation ability in LCN2-deleted Caki-1 cells. (D-E) Colony formation assay was performed to detect cell colony formation ability of restoring the expression of LCN2 in PRMT1-deleted Caki-1 cells. (F-G) SRB assay was performed to detect cell proliferation of knocking down of PRMT1 in LCN2-deleted Caki-1 cells. (H-I) SRB assay was performed to detect cell proliferation of DCPT1061 treated and/or LCN2 deleted Caki-1 cells. *P < 0.05, **P < 0.01, and ***P < 0.001.