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. 2021 Mar 3;12(4):555–562. doi: 10.1021/acsmedchemlett.0c00547

Figure 3.

Figure 3

(Top) Detailed view of compound 22 bound to the ATP binding site of TAK1. (Bottom) Overlay of several X-rays of TAK1 with type-I binding compounds (gray) (PDB ID codes: 2EVA, 4L53, 5JGD, and 5V5N) and compound 22 structure (green).