Table 2.
Role of anthrax toxin receptor 1 in different kinds of cancer
Different kinds of cancer
|
Summary of findings
|
Ref.
|
Gastric cancer | Overexpress in gastric adenocarcinoma | Sotoudeh et al[11] |
Active the PI3K/AKT/mTOR signaling pathway | Cai et al[19] | |
It is the potent antigenic targets for CAR T cell therapy | Sotoudeh et al[18] | |
Colorectal cancer | Influence tumor development by disrupting tumor vasculature. | Fernando et al[20] |
It possible use as biomarkers for screening, diagnosis, and therapy | Pietrzyk et al[21] | |
Lung cancer | It regulates the proliferation, apoptosis, migration and invasion of lung cancer cells. | Gong et al[22] |
It is an excellent indicator for early clinical diagnosis and prognosis of lung cancer. | Sun et al[23] | |
Breast cancer | It enhances tumor immunity in conjunction with immunization against differentiation ag. | Felicetti et al[24] |
It expression in triple-negative breast cancer. | Gutwein et al[25] | |
It enhances tumor growth and metastasis in breast cancer cells. | Opoku-Darko et al[26] | |
ANTXR1-Specific CAR T cells as a targeted therapy for breast cancer. | Byrd et al[27] |