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. 2021 Apr 6;14:1519–1531. doi: 10.2147/DMSO.S302621

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© 2021 De Nigris et al.

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Teneligliptin, but not sitagliptin, reduces M1 and enhances M2 population by enhancing eNO under HG-HM conditions. (A) Experimental design. (B) NO levels. Fold changes in expression levels of (C) M1 markers (Tnf-α, Mcp-1 and Rantes) and (D) M2 markers (Arg1, Chi3l3 and Mgl2). For all diagrams, error bars are ± SEM and * ANOVA p < 0.05, ** ANOVA p < 0.01, *** ANOVA p < 0.001, **** ANOVA p < 0.0001; n = 5. Abbreviations: SITA, sitagliptin; TNG, teneligliptin.