Figure 3.

Assessment of cytotoxicity after treatment of cancer cells with 599 or its peptide variants in complex with siRNA

The long-term cellular toxicity (as measured by a cell proliferation assay) of CAL 27 cancer cells was assessed 48 h post-treatment with 599 or its peptide variants in complex with a non-targeting siRNA (siNT) at 50:1 Peptide:siRNA molar (12.5 N/P) ratios. Data are mean ± SEM of three independent samples, where p ≥ 0.05 is not significant (ns) compared to 599 (1-way ANOVA).