Table 2.
Lid margin abnormality, meibomian gland function, and meibomian gland dysfunction stage before and after eyelid debris debridement and meibomian gland expression in patients with moderate and severe meibomian gland dysfunction
| Parameters | Before treatment | 4 weeks after the treatment | P value |
|---|---|---|---|
| Lid margin abnormality | |||
| Lid margin irregularitya | |||
| UL (0–2) | 1.57 (0.07) | 1.32 (0.08) | 0.047 |
| LL (0–2) | 1.57 (0.07) | 1.36 (0.09) | 0.117 |
| Telangiectasiaa | |||
| UL (0–3) | 1.96 (0.07) | 1.37 (0.10) | < 0.001 |
| LL (0–3) | 1.96 (0.07) | 1.43 (0.10) | < 0.001 |
| Meibomian gland orifice plugginga | |||
| UL (0–2) | 1.79 (0.07) | 1.05 (0.09) | < 0.001 |
| LL (0–2) | 1.75 (0.09) | 1.09 (0.09) | < 0.001 |
| Thicknessa | |||
| UL (0–2) | 1.60 (0.07) | 1.02 (0.08) | < 0.001 |
| LL (0–2) | 1.54 (0.07) | 1.07 (0.09) | < 0.001 |
| Mucocutaneous junction replacementb | 26 (56.5%) | 18 (40.9%) | 0.115 |
| Meibum characteristics | |||
| Meibum colora | |||
| UL (1–3) | 1.92 (0.07) | 1.66 (0.09) | 0.026 |
| LL (1–3) | 1.96 (0.09) | 1.48 (0.08) | < 0.001 |
| Meibum consistencya | |||
| UL (1–3) | 1.69 (0.09) | 1.25 (0.07) | < 0.001 |
| LL (1–3) | 1.65 (0.07) | 1.23 (0.06) | < 0.001 |
| Meibum gradeb | |||
| UL (0–3) | 38 (79.2%) | 12 (25.0%) | < 0.001 |
| MGD stageb | 39 (84.8%) | 10 (21.7%) | < 0.001 |
MGD meibomian gland dysfunction, UL upper lid, LL lower lid
aResults are presented as mean (standard error) and P values are from linear mixed model
bGeneralized estimating equations model for noncontinuous scale values: mucocutaneous junction replacement, n (%, proportion for positive result), meibum grade, n (%, proportion ≥ grade 2), MGD stage, n (%, proportion ≥ stage 3)