Table 1: Patient Demographics and Endpoints.
Demographics, prior treatments, duration on treatment, and reasons for coming off treatment for all study patients.
| Characteristic | Patients n (%) |
|---|---|
| Median age, years (range) | 60 (34–73) |
| Gender | |
| Female, no. (%) | 10 (40) |
| Male, no. (%) | 15 (60) |
| Ethnicity, no. (%) | |
| White | 24 (96) |
| Black | 1 (4) |
| Type of primary tumor, no. (%) | |
| Pancreatic adenocarcinoma | 21 (84) |
| Peritoneal mesothelioma | 1 (4) |
| Cervical carcinoma | 1 (4) |
| Ampullary adenocarcinoma | 1 (4) |
| Cancer of unknown primary | 1 (4) |
| Karnofsky performance status, no. (%) | |
| 100 | 5 (20) |
| 90 | 18 (72) |
| 80 | 2 (8) |
| ECOG Score | |
| 0 | 23 (92) |
| 1 | 2 (8) |
| # of Prior Chemotherapy Treatments | |
| 0 | 17 (68) |
| 1 | 3 (12) |
| 2 | 1 (4) |
| 3 | 4 (16) |
| Prior Radiation Therapy Without Concurrent Chemotherapy | |
| 0 | 24 (96) |
| 1 | 1 (4) |
| Number of Prior Combination Chemoradiation | |
| 0 | 17 (68) |
| 1 | 7 (28) |
| 2 | 1 (4) |
| Total # of Prior Treatments | |
| 0 | 12 (48) |
| 1 | 6 (24) |
| 2 | 2 (8) |
| 3 | 3 (12) |
| 4 | 2 (8) |
| Median time on therapy in days (range) | 56 (1, 273) |
| Mean number of cycles on therapy (range) | 2.9 (0.04–9.7) |
| Reason Off Treatment | |
| Intercurrent illness | 5 (21) |
| Noncompliance | 1 (4) |
| Progression of disease | 12 (50) |
| Patient choice | 1 (4) |
| Toxicity | 5 (21) |