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. 2021 Mar 2;17(4):1026–1040. doi: 10.7150/ijbs.55559

Figure 8.

Figure 8

Protein-protein interaction in the PI3K-AKT signalling pathway and ECM-receptor interactions. A. ECM-receptor interaction pathway was adapted from KEGG; the red box indicates the upregulated genes. B. Protein-protein interaction network of genes enriched in the PI3K-AKT signalling pathway and ECM-receptor interactions. The core proteins were FN1, VEGFA, COL1A1, IL6, CD4, and PDGFRB.