Identification of differentially expressed proteins during human gastric mucosal carcinogenesis by proteomics analysis. (A) LCM of purified NGM, AH, GPDAC and LMGAC tissues. (B) MS/MS maps for identifying peptides of PRSS1 and relative quantitative information of PRSS1 expression in four different tissues. (C) A regulatory network of gastric mucosa carcinogenesis-related proteins. LCM, laser capture microdissection; NGM, normal gastric mucosa; AH, atypical hyperplasia; GPDAC, poorly differentiated gastric adenocarcinoma; LMGAC, lymph node metastasis adenocarcinoma.