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. 2021 Mar 11;17(4):1138–1152. doi: 10.7150/ijbs.57825

Figure 5.

Figure 5

Inhibition of autophagy reverses the effects of BA on functional recovery after SCI. (A) Longitudinal spinal cord sections from the indicated groups at day 14 were analyzed by HE staining and Masson staining (scale bar=1000 µm). (B) Quantitative analysis of Masson positive lesions in the spinal cords of each group. (C) Images (30×) of the spinal cord sections in each group stained with antibodies against MAP2 (scale bar = 25 µm). (D) The optical density of MAP2 in the injured spinal cord at day 28. (E) Images (150×) of spinal cord sections below the injury (T11-T12) stained at day 28 with antibodies against SYN/NeuN (scale bar = 5 µm). (F) Corresponding quantification of the number of synapses contacting motor neurons. (G) Photos of mice footprints at day 28 after SCI. (H) Basso mouse scale (BMS) for the indicated groups and time points. The values are expressed as the means ± SEM, n=5 per group. *p< 0.05 and **p< 0.01, vs. BA group.