Table 1.

Docking details between the compound and the target proteins

Targets	PDB code	LiDock Score	Groups of comp.	Amino acid	Bonds name
GPX4	6hkq	72.39	OH	Glycine	Unfavorable Donor-Donor
			Benzene ring	Lysine	Pi-Alkyl
			OH	Lysine	Unfavorable Donor-Donor
			OH	Arginase	Conventional Hydrogen Bond
			OH	Alanine	Conventional Hydrogen Bond
			OH	Glycine	Carbon Hydrogen Bond
			Benzene ring	Isoleucine	Carbon Hydrogen Bond
TP53	3zme	75.53	OH	Cystine	Conventional Hydrogen Bond
			OH	Glutamic	Conventional Hydrogen Bond
			OH	Proline	Pi-Donor Hydrogen Bond
			Benzene ring	Glutamic	Pi-Anion
			OH	Threonine	Conventional Hydrogen Bond
			Benzene ring	Threonine	Carbon Hydrogen Bond
			Carbonyl	Threonine	Vander waals
TRFC	6y76	68.03	Benzene ring	Lysine	Pi-Alkyl
			OH	Tyrosine	conventional Hydrogen Bond
			OH	Lysine	Unfavorable Donor-Donor
			OH	Serine	Unfavorable Donor-Donor
			OH	Asparagine	Unfavorable Donor-Donor
			Carbonyl	Asparagine	Conventional Hydrogen Bond
AURKA	3p9j	66.87	OH	Phenylalanine	Unfavorable Donor-Donor
			Benzene ring	Aspartic	Pi-Anion
			OH	Aspartic	Conventional Hydrogen Bond
ATF4	1ci6	67.1	Benzene ring	Lysine	Pi-Alkyl
			Benzene ring	Alanine	Pi-Alkyl
			OH	Glutamine	Conventional Hydrogen Bond
			OH	Asparagine	Conventional Hydrogen Bond
			OH	Glutamine	Conventional Hydrogen Bond
NRF2	3zgc	69.2	OH	Histidine	Conventional Hydrogen Bond
			OH	Asparagine	Unfavorable Donor-Donor
			Benzene ring	Asparagine	Pi-Anion
			O	Asparagine	Conventional Hydrogen Bond
			O	Asparagine	Unfavorable Donor-Donor
SIGMAR1	6djz	86.4	Benzene ring	Arginine	Pi-Alkyl
			Benzene ring	Methionine	Pi-Sulfur
			Benzene ring	Tryptophan	Pi-Sulfur
			OH	Arginine	Conventional Hydrogen Bond
			OH	Arginine	Unfavorable Donor-Donor
CDKN2A	1dc2	N/A
PRNP	3hjx	N/A