Fig. 1.
Representative implementations of PAT. (A) PACT. (B) AR-PAM. (C) and (C-2) Transmitted and epi-illumination OR-PAM. (D) OAMes. EX, excitation light. AW, acoustic wave. UST, ultrasonic transducer. VD, virtual detector. (E) Cerebral vasculature of a rat obtained by PACT (11 mm in depth). [3]. (F) In vivo AR-PAM imaging of a mouse brain (3.2 mm in depth) [18]. (G) Cerebral vasculature of a mouse obtained by high resolution OR-PAM (more than 200 μm in depth) [19]. (H) The cross-section image (top) of healthy skin and MAPs of different skin layers (bottom). EP, epidermis. CL, capillary loops. VP, vascular plexus. DR, dermis (5 mm in depth) [19]. (I) Comparison of resolution and penetration depth between PACT, OAMes, and PAM. Reprinted with permission from Ref. [3,[18], [19], [20]].