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. Author manuscript; available in PMC: 2022 May 1.
Published in final edited form as: Auton Neurosci. 2021 Mar 11;232:102796. doi: 10.1016/j.autneu.2021.102796

Figure 5: Heart rate baroreflex function is impaired in ETB-def rats compared to TG controls.

Figure 5:

A: RSNA composite baroreflex curves. B: heart rate composite baroreflex curves. C: RSNA composite gain curves from first derivative of baroreflex curve. D. heart rate composite gain curves from first derivative of baroreflex curve. (A-D) a = TG NS; b = ETB-def NS; c = TG HS; d = ETB-def HS E. Linear regression of RSNA response to increase in pressure during phenylephrine, 2-way ANOVA Psalt = 0.0309; Pgenotype = 0.0030; Pinteraction = 0.8601, with Sidak’s test for multiple comparisons (no significant differences). F. Linear regression of heart rate response to increase in pressure during phenylephrine, 2-way ANOVA Psalt = 0.0298; Pgenotype = 0.0044; Pinteraction = 0.0400, with Sidak’s test for multiple comparisons. p values in (). RSNA = renal sympathetic nerve activity, MAP = mean arterial pressure, IBI = interbeat interval.