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. 2021 Mar 11;18(9):2051–2062. doi: 10.7150/ijms.51497

Figure 1.

Figure 1

TIPE2 expression and clinical significance in normal pancreatic tissues and early/advanced tumor tissues. a. IHC results (×100 magnification and ×200 magnification) of TIPE2 expression in adjacent normal tissues and early and advanced PDAC tissues. b. TIPE2 expression was upregulated in early PDAC tissues compared to adjacent healthy tissue. ***P<0.001. c. TIPE2 expression was lower in advanced PDAC tissues compared to normal pancreatic tissue. ***P<0.001. d. The ROC curve shows clear separation between normal tissues and early PDAC tissues with an AUC of 0.754 (P<0.01). e. The ROC curve shows strong separation between adjacent normal tissues and advanced PDAC tissues with an AUC of 0.726 (P<0.01).