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. 2021 Mar 11;18(9):2051–2062. doi: 10.7150/ijms.51497

Figure 2.

Figure 2

Expression and significance of TIPE2 in tumor tissues with and without lymph node metastasis (LNM). Kaplan‑Meier survival curves of patients with PDAC. a. IHC results (×100 magnification and ×200 magnification) of TIPE2 expression in PDAC tissues with and without LNM. b. Expression of TIPE2 was higher in PDAC tumor tissue without LNM compared to PDAC tumor tissue with LNM. ***P<0.001. c. The ROC curve shows separation between PDAC tumor tissues with and without LNM with an AUC of 0.804 (P<0.001). d-e. A log-rank test revealing the significant effect of tumor grade (d) and the level of TIPE2 (e) on the overall survival time of the patients. f-g. TIPE2 expression in PDAC tissues during progressor and non-progressor were measured by qPCR. h-i. The expression of TIPE2 in the adjacent normal tissues and PDAC tissues were detected by western blot analysis.