Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2021 Mar 15;17(5):1178–1190. doi: 10.7150/ijbs.57783

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The author(s)

This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/). See http://ivyspring.com/terms for full terms and conditions.

PMC Copyright notice

Characterization of circMETTL3 in breast cancer cells and tissues. A. Sanger sequencing-validated circular structure. Arrows indicated the junction site of circMETTL3. B. RT-PCR analysis for circMETTL3 and its linear transcript METTL3 in cDNA and gDNA in breast cancer cells. C. qRT-PCR analysis of circMETTL3 and METTL3 after treatment with actinomycin D at the indicated time points. D. qRT-PCR showed the expression of circMETTL3 and METTL3 mRNA in breast cancer cells treated with RNase R or mock control. E. Expression of circMETTL3 in the breast cancer cell lines and MCF-10A by qRT-PCR. F. Expression of circMETTL3 in breast cancer tissues and adjacent normal tissues. Data were shown as mean ± SD. *p <0.05, **p <0.01, ***p<0.001.