Figure 3.

circMETTL3 enhances breast cancer cells migration and invasion ability. A-B. The wound healing assays were performed to assess the effect of circMETTL3 on cell motility at 0 and 48 h in ZR-75-1 (A) and SUM1315 (B) cell lines. Scale bar, 100 µm. C-D. The representative images of migrated (C) and invaded (D) ZR-75-1 and SUM1315 cell lines after circMETTL3 knockdown. Scale bar, 100 µm.si-NC indicates negative control, si-1 indicates si-circMETTL3-1,si-2 indicates si-circMETTL3-2. Data were shown as mean ± SD, *p <0.05, **p <0.01, ***p<0.001.