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Inhibition of SIRT3 prevents Ti particle-induced osteolysis and bone loss in vivo. (A) Micro-CT analyses of calvaria samples from the indicated treatment groups. (B) Bone mineral density (BMD) values, (C) bone volume/tissue volume (BV/TV) values, (D) percentage of porosity and (E) number of porosity were quantified to assess bone microstructure. Data are means ± SD (*p <0.05, **p <0.01, *** p <0.005, n=5).
