Table 1.
Schedule of data collection in the MAVIDOS trial.
| Pregnancy | Birth | Childhood follow up | |||||||
|---|---|---|---|---|---|---|---|---|---|
| 14 weeks | 18–21 weeks | 34 weeks | Birth | 1 year | 2 years | 3 years | 4 years | 6–8 years | |
| Mother | |||||||||
| Anthropometry | x | x | x | ||||||
| Health, diet and lifestyle questionnaire | x | x | |||||||
| Blood sampling | x | x | |||||||
| Tablet count to assess compliance | x | x | x | ||||||
| Foetal ultrasonography | x | ||||||||
| DXA | x | x | |||||||
| pQCT | x | ||||||||
| Father | |||||||||
| Anthropometry | x* | x* | x* | ||||||
| Placenta | |||||||||
| Placental and cord tissue collected | x | ||||||||
| Offspring | |||||||||
| Anthropometry | x | x | x | x | x | x | |||
| Health, diet and lifestyle questionnaire | x | x | x | x | x | ||||
| DXA | x | x | x | ||||||
| pQCT | x | ||||||||
| HRpQCT | x | ||||||||
| Hand-grip strength | x | x | |||||||
| Blood sampling | x (cord blood) | x | x | ||||||
x denotes data collected at this time point.
*
Measurement obtained once at one of these visits.
DXA, dual-energy X-ray absorptiometry; HRpQCT, high-resolution peripheral quantitative computed tomography; MAVIDOS, Maternal Vitamin D Osteoporosis Study; pQCT, peripheral quantitative computed tomography.