Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Poisson distributions of peaks per microparticle in model assay. The readout of HDIA is always ratiometric (signal/area), but defining an area equivalent to a single microparticle allows the data to be fit to Poisson distributions. The histograms show detected peaks per microparticle for three SAPE concentrations: (A) 144 fM, (B) 48 fM, and (C) 16 fM. The fits show excellent agreement, signifying discrete signals (i.e., single antibody sandwich detection). n = 216.
