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Magnetically based directed cell cluster formation. (A–D) Raw264.7 cells were incubated with magnetic nanoparticles at 500 µg/mL and analysed after 24 h incubation in an inverted microscope for magnetically based cluster formation. (B and C) In presence of the magnet system M3, SPION-loaded cells aggregate and form long pole-ladder like structures. (D) These structures were largely reversible, although some of them remained present after removing the magnet system.
