Table 1.
Characteristics of subjects in the training cohort and the positive detection rates of mSFRP2, mSDC2 and SpecColon test by different cut-off values
| Group | Number (n) | Age (years) | Gender (%) | Positive detection rate (%) | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Mean (Min-Max) | Male | Female | Cut-off-1 | Cut-off-2 | |||||||
| mSFRP2 | mSDC2 | SpecColon | mSFRP2 | mSDC2 | SpecColon | ||||||
| Normal | 123 | 46.9 (23-83) | 53.7 | 46.3 | 13.0 | 1.6 | 13.0 | 5.7 | 1.6 | 6.5 | |
| CRC | 111 | 60.8 (27-84) | 56.8 | 43.2 | 84.7 | 74.8 | 89.2 | 71.2 | 74.8 | 83.8 | |
| 0 | 3 | 52.0 (38-67) | 0.0 | 100.0 | 66.7 | 66.7 | 100.0 | 66.7 | 66.7 | 100.0 | |
| I | 20 | 62.9 (43-79) | 44.5 | 55.5 | 85.0 | 75.0 | 95.0 | 70.0 | 75.0 | 90.0 | |
| II | 32 | 61.0 (35-82) | 68.7 | 31.3 | 87.5 | 81.3 | 87.5 | 84.4 | 81.3 | 87.5 | |
| III | 37 | 60.7 (27-83) | 56.8 | 43.2 | 81.1 | 75.7 | 86.5 | 64.9 | 75.7 | 83.8 | |
| IV | 10 | 58.9 (41-75) | 40.0 | 60.0 | 90.0 | 60.0 | 90.0 | 50.0 | 60.0 | 60.0 | |
| Unknown | 9 | 60.6 (43-84) | 44.4 | 55.6 | 88.9 | 66.7 | 88.9 | 77.8 | 66.7 | 77.8 | |
| Polyp | |||||||||||
| AA | 13 | 58.8 (46-75) | 69.2 | 30.8 | 58.8 | 46.2 | 61.5 | 30.8 | 46.2 | 53.8 | |
| SP | 44 | 55.5 (24-75) | 68.2 | 31.8 | 38.6 | 13.6 | 40.9 | 31.8 | 13.6 | 34.1 | |