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. 2021 Mar 10;12(9):2768–2776. doi: 10.7150/jca.51434

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CIK cells could carry KGHV500. (A and B) CIK cell markers CD3 and CD56 were detected by IHC. Bar: 100 µm. (C) CD46 on the surface of CIK cells was detected by IHC. Bar: 100 µm. (D) The adenovirus hexon was detected in CIK cells by IHC. Bar: 100 µm. Strong staining was marked by arrows. (E and F) Electron microscopy showed that many virus particles accumulated on CIK cell membrane (marked by arrows). Bar: 500 nm. (G-J) Flow cytometry of CD3 and CD56 expression of CIK cells before and after KGHV500 infection.