Table 1.
Prevalence of gastrointestinal (GI) symptoms in COVID-19 patients
| Title | Authors | PMID | Total studies included | Total patients across all studies | Diarrhea, % (n if available) | Abdominal pain, % (n if available) | Vomiting and nausea, % (n if available) | All GI symptoms, % (n if available) | Dates for which data obtained |
|---|---|---|---|---|---|---|---|---|---|
| Gastrointestinal manifestations of SARS-CoV-2 infection and virus load in fecal samples from a Hong Kong cohort: systematic review and meta-analysis | Cheung et al. 2020 | 32251668 | 60 | 4,243 | 12.5% [95% CI, 9.6%–16.0%] (326/3536) | 9.2% [95% CI, 5.7%–14.5%] (52/751) | 10.2% [95% CI, 6.6%–15.3%] (210/751) | 17.6% [95% CI, 12.3%–24.5%] | Onset–March 11, 2020 |
| Prevalence of gastrointestinal symptoms in coronavirus disease 2019: a meta-analysis | Merola et al. 2020 | 33321018 | 33 | 4,434 | 7.78% [95% CI, 5.05%–11.04%] | NR | 3.57% [95% CI, 1.87%–5.80%] | 11.51% [95% CI, 8.16%–15.35%] (537/4243) | Onset–March 25, 2020 |
| AGA Institute rapid review of the gastrointestinal and liver manifestations of COVID-19, meta-analysis of international data, and recommendations for the consultative management of patients with COVID-19 | Sultan et al. 2020 | 32407808 | 47 | 10,890 | 7.7% [95% CI, 7.2%–8.2%] (822/10,676) | 2.7% [95% CI, 2.0%–3.4%] (108/4031) | 7.8% [95% CI, 7.1%–8.5%] (465/5955) | NR | Onset–April 19, 2020 |
| Prevalence of gastrointestinal symptoms and fecal viral shedding in patients with coronavirus disease 2019: a systematic review and meta-analysis | Parasa et al. 2020 | 32525549 | 29 | 4,805 | 7.8% [95% CI, 5.1%–11.9%] | NR | 3.9% [95% CI, 2.1%–7.2%] | NR | Onset–March 30, 2020 |
| Duration of respiratory and gastrointestinal viral shedding in children with SARS-CoV-2: a systematic review and synthesis of data | Xu et al. 2020 | 32618932 | 17 | 69 (pediatric) | NR | NR | NR | 17.4% (12) | Onset–May 8, 2020 |
| Gastrointestinal symptoms and fecal nucleic acid testing of children with 2019 coronavirus disease: a systematic review and meta-analysis | Wang et al. 2020b | 33082472 | 38 | 3,028 (pediatric) | NR | NR | NR | 17.7% [95% CI, 13.9%–21.5%] (536) | January 1–August 10, 2020 |
As reported on PubMed prior to January 19, 2021.
(PMID) PubMed Identifier, (CI) confidence interval, (NR) not reported.