Table 2.
Clinical characteristics of patients with COVID-19 with ARDS according to status at D28
| Survivors (n = 26) | Non-survivors (n = 14) | p value | |
|---|---|---|---|
| Demographics | |||
| Age | 65 [55–70] | 67 [58–78] | 0.3076 |
| Gender | 23 (88%) | 13 (93%) | > 0.9999 |
| Body mass index (kg/m2) | 30 [27–35] | 28 [24–30] | 0.0960 |
| Body mass index > 30 kg/m2 | 14 (54%) | 3 (21%) | 0.0921 |
| Delay between first symptoms (Days) | 7 [4–12] | 5 [4–9] | 0.1909 |
| Comorbidities | |||
| Comorbidities | 0.3202 | ||
| 0 | 15 (58%) | 5 (36%) | |
| ≥ 1 | 11 (42%) | 9 (64%) | |
| Charlson score | 0 [0–2] | 2 [0–2] | 0.1281 |
| Severity scores | |||
| SOFA score | 8 [3–10] | 8 [4–8] | 0.7937 |
| SAPS II score | 41 [31–52] | 40 [33–59] | 0.5893 |
| PaO2/FiO2 at admission | 150 [94–169] | 116 [94–162] | 0.2993 |
| ARDS severity mild | 1 (4%) | 1 (7%) | > 0.9999 |
| Moderate | 18 (69%) | 9 (64%) | > 0.9999 |
| Severe | 7 (27%) | 4 (29%) | > 0.9999 |
| Follow-up | |||
| Days in ICU | 40 [16–76] | 11 [6–20] | 0.0008 |
| Days in hospital | 64 [38–77] | 15 [7–20] | < 0.0001 |
| Secondary infections | 21 (81%) | 9 (64%) | 0.2777 |
The results are shown as medians and interquartile ranges [Q1–Q3] for continuous variables or numbers and percentage for categorical variables. COVID-19 patients with ARDS were separated in two groups based on status at D28 after admission. Sepsis-related organ failure assessment (SOFA) and simplified acute physiology score II (SAPS II) scores were calculated during the first 24 h after admission. Patients were classified in ARDS severity groups according to Berlin criteria. ICU: intensive care unit. Data were compared using nonparametric Mann–Whitney test for continuous variables or Fisher’s exact test for categorical variables
p values inferior to 0.05 are highlighted in bold