Table 1.
GO and KEGG pathway enrichment analysis of DEmRNAs.
| Term ID | Term description | Observed counts | FDR |
|---|---|---|---|
| Biological processes | |||
| GO:0009888 | Tissue development | 46 | 1.95E-09 |
| GO:0007275 | Multicellular organism development | 76 | 2.91E-06 |
| GO:0008544 | Epidermis development | 19 | 2.91E-06 |
| GO:0048856 | Anatomical structure development | 80 | 2.91E-06 |
| GO:0048513 | Animal organ development | 55 | 4.84E-06 |
| GO:0030855 | Epithelial cell differentiation | 23 | 6.93E-06 |
| GO:0043588 | Skin development | 17 | 1.66E-05 |
| GO:0060429 | Epithelium development | 29 | 1.66E-05 |
| GO:0030154 | Cell differentiation | 59 | 2.35E-05 |
| GO:0032501 | Multicellular organismal process | 90 | 2.35E-05 |
| Cell component | |||
| GO:0005576 | Extracellular region | 50 | 3.20E-06 |
| GO:0044464 | Cell part | 161 | 1.60E-04 |
| GO:0031012 | Extracellular matrix | 11 | 3.50E-03 |
| GO:0071944 | Cell periphery | 69 | 3.70E-03 |
| GO:0005886 | Plasma membrane | 67 | 6.40E-03 |
| GO:0045171 | Intercellular bridge | 5 | 8.50E-03 |
| GO:0001533 | Cornified envelope | 5 | 1.05E-02 |
| GO:0099081 | Supramolecular polymer | 19 | 1.05E-02 |
| GO:0009986 | Cell surface | 16 | 1.15E-02 |
| GO:0005622 | Intracellular | 141 | 2.49E-02 |
| Molecular function | |||
| GO:0043394 | Proteoglycan binding | 5 | 9.20E-03 |
| GO:0005200 | Structural constituent of cytoskeleton | 7 | 1.51E-02 |
| GO:0005504 | Fatty acid binding | 4 | 1.51E-02 |
| GO:0005515 | Protein binding | 82 | 1.51E-02 |
| GO:0031406 | Carboxylic acid binding | 9 | 1.51E-02 |
| GO:0033293 | Monocarboxylic acid binding | 5 | 1.64E-02 |
| GO:0050786 | RAGE receptor binding | 3 | 1.64E-02 |
| GO:0001228 | DNA-binding transcription activator activity | 12 | 1.87E-02 |
| GO:0036041 | Long-chain fatty acid binding | 3 | 1.87E-02 |
| GO:1990837 | Sequence-specific double-stranded DNA binding | 17 | 1.87E-02 |
| KEGG | |||
| hsa05219 | Bladder cancer | 6 | 4.80E-04 |
| hsa04512 | ECM-receptor interaction | 7 | 8.70E-04 |
| hsa03320 | PPAR signaling pathway | 6 | 2.90E-03 |
| hsa05200 | Pathways in cancer | 15 | 2.90E-03 |
| hsa04657 | IL-17 signaling pathway | 6 | 6.50E-03 |
| hsa05206 | Micrornas in cancer | 7 | 1.09E-02 |
| hsa04610 | Complement and coagulation cascades | 5 | 1.72E-02 |
| hsa04514 | Cell adhesion molecules (cams) | 6 | 2.77E-02 |
| hsa04974 | Protein digestion and absorption | 5 | 2.77E-02 |
| hsa05146 | Amoebiasis | 5 | 2.77E-02 |
| hsa05222 | Small cell lung cancer | 5 | 2.77E-02 |
| hsa00590 | Arachidonic acid metabolism | 4 | 3.20E-02 |