Table 1.
Characteristics of patients
| Characteristics | ExosomalmiR-1305 | P value | |
|---|---|---|---|
| Low (n = 21) | High (n = 21) | ||
| Age | |||
| < 60 | 11 (52) | 9 (43) | 0.758 |
| ≥ 60 | 10 (48) | 12 (57) | |
| Sex | |||
| Male | 10 (48) | 10 (48) | > 0.999 |
| Female | 11 (52) | 11 (52) | |
| ISS | |||
| Low | 7 (33) | 10 (48) | 0.580 |
| Intermediate | 9 (43) | 8 (38) | |
| High | 5 (24) | 3 (14) | |
| Serum LD | |||
| Normal | 9 (43) | 15 (71) | 0.137 |
| Increased | 11 (52) | 6 (29) | |
| Unknown | 1 (5) | 0 (0) | |
| Bone marrow plasma cell | |||
| < 30% | 8 (38) | 8 (38) | > 0.999 |
| ≥ 30% | 13 (62) | 13 (62) | |
| Deletion 13 | |||
| Absence | 9 (43) | 16 (76) | 0.076 |
| Presence | 9 (43) | 3 (14) | |
| Unknown | 3 (14) | 2 (10) | |
| Deletion 17p | |||
| Absence | 17 (81) | 19 (90) | 0.519 |
| Presence | 1 (5) | ||
| Unknown | 3 (14) | 2 (10) | |
| Translocation (4;14) | |||
| Absence | 14 (67) | 18 (86) | 0.287 |
| Presence | 4 (19) | 1 (5) | |
| Unknown | 3 (14) | 2(10) | |
| Translocation (11;14) | |||
| Absence | 9 (43) | 11 (52) | 0.549 |
| Presence | 3 (14) | 1 (5) | |
| Unknown | 9 (43) | 9 (43) | |
| Translocation (14;16) | |||
| Absence | 18 (86) | 19 (90) | > 0.999 |
| Presence | 0 (0) | 0 (0) | |
| Unknown | 3 (14) | 2 (10) | |
| Translocation (14;20) | |||
| Absence | 13 (62) | 10 (48) | 0.536 |
| Presence | 0 (0) | 0 (0) | |
| Unknown | 8 (38) | 11 (52) | |
| First-line induction treatment | |||
| Bortezomib-based treatment | 14 (67) | 12 (57) | 0.751 |
| Thalidomide-based treatment | 7 (33) | 9 (43) | |
| Autologous stem cell transplantation | |||
| Done | 15 (71) | 11 (52) | 0.341 |
| Not done | 6 (29) | 10 (48) | |
| Survival status | |||
| Alive | 15 (71) | 8 (38) | 0.062 |
| Dead | 6 (29) | 13 (62) | |