Table 2.
Univariate and multivariate analysis of clinicopathological variables for overall survival rate in 285 gastric cancer patients
Clinical parameters | Univariate analysis | P value | Multivariate analysis | p value |
---|---|---|---|---|
HR (95%CI) | HR (95%CI) | |||
Gender (female vs. male) | 0.93 (0.73-1.20) | 0.780 | ||
Age (≥60 vs. <60) | 0.84 (0.65-1.08) | 0.183 | ||
Tumor size (≥3 cm vs. <3 cm) | 1.29 (1.00-1.66) | 0.047 | 1.06 (0.82-1.38) | 0.649 |
Histological grade (poor vs. well to mod.) | 1.19 (0.92-1.53) | 0.179 | ||
Primary tumor category (T1/T2 vs. T3/T4) | 0.55 (0.43-0.70) | <0.001 | 0.55 (0.42-0.72) | <0.001 |
Lauren type (diffuse/mix vs. intestinal) | 1.58 (1.15-2.32) | 0.001 | 1.64 (1.23-2.17) | 0.001 |
TNM stage (III-IV vs. I-II) | 1.13 (1.02-1.34) | 0.046 | 0.98 (0.69-1.38) | 0.894 |
CXCL12 CAF (positive/negative) | 1.38 (1.07-1.76) | 0.012* | 1.50 (1.16-1.93) | 0.002* |
Wnt5a (positive/negative) | 1.10 (1.41-1.81) | 0.007* | 1.28 (0.99-1.66) | 0.060* |
*Statistically significantly.