Table 4.
Summary of the Cox regression model for the results of a multivariate analysis of demographics, clinical data, laboratory test, and survival time of severe COVID-19 patients in ICU.
| Factors | p value | Hazard ratio | 95% CI |
|---|---|---|---|
| Age (years) 20–39 | 0.04 | 2.73 | 1.046–7.195 |
| 40–59 | 0.024 | 2.532 | 1.133–5.657 |
| 60–79 | <0.001 | 4.447 | 1.948–10.153 |
| ≥ 80 | — | — | — |
| Sex (female) | 0.005 | 2.355 | 1.301–4.264 |
| Diabetes (yes) | 0.005 | 2.178 | 1.263–3.757 |
| AST (increased) | <0.001 | 4.346 | 2.088–9.044 |
| Bilirubin nonconjugated (increased) | 0.327 | 1.484 | 0.674–3.267 |
| Creatinine (increased) | 0.007 | 6.501 | 1.677–25.194 |
| BUN (increased) | 0.447 | 1.763 | 0.369–8.427 |
| Neutrophils (increased) | 0.634 | 1.302 | 0.401–4.480 |
| Eosinophils (decreased) | 0.017 | 2.211 | 1.155–4.234 |
| Basophils (decreased) | 0.368 | 1.426 | 0.658–3.093 |
| Monocytes (decreased) | 0.343 | 1.302 | 0.755–2.245 |
| Lymphocytes (decreased) | 0.894 | 1.124 | 0.202–6.244 |
Symbol “—” indicates unmeasurable values due to linearity issues in the original data. AST: aspartate aminotransferase; BUN: blood urea nitrogen.