Table 1.
Inclusion criteria of studies to assess medical abortion effectiveness after systemic hormonal contraception (HC)* initiation and safety of systemic HC initiation after abortion
| Population | Intervention | Comparison | Outcome(s) | Included studies |
|---|---|---|---|---|
| Medical abortion | ||||
| Individuals undergoing medical abortion | Immediate HC initiation | Delayed HC initiation | Abortion success Adverse events |
5 (4 RCTS, 1 cohort) |
| Individuals undergoing medical abortion | HC initiation at any time | No HC initiation | Abortion success Adverse events |
5 (3 RCTs, 2 cohort) |
| Surgical abortion | ||||
| Individuals undergoing surgical abortion | Immediate HC initiation | Delayed HC initiation | Adverse events | 1 RCT |
| Individuals undergoing surgical abortion | HC initiation at any time | No HC initiation | Adverse events | 6 cohort |
| Spontaneous abortion | ||||
| Individuals with spontaneous abortion | Immediate HC initiation | Delayed HC initiation | Adverse events | None |
| Individuals with spontaneous abortion | HC initiation at any time | No HC initiation | Adverse events | None |
| Septic abortion | ||||
| Individuals with septic abortion | Immediate HC initiation | Delayed HC initiation | Adverse events | None |
| Individuals with septic abortion | HC initiation at any time | No HC initiation | Adverse events | None |
RCT, randomized controlled trial.
*HC, hormonal contraception is defined as systemic hormonal contraception and includes combined hormonal methods (oral, patch, ring, or injectable) and progestogen-only methods (oral, injectable, or implant).