FIG 3.

False-negative findings of the DLM (A–D, white arrows) as shown in a 67-year-old male patient (A, same patient as in Fig 2; metastasis volume: 0.004 cm³), a 56-year-old male patient (B and C, metastases volume: 0.008 and 0.01 cm³), and a 62-year-old male patient (E, metastasis volume: 0.016 cm³) with malignant melanoma. As demonstrated, the DLM missed small metastases. Examples of false-positive findings of the DLM (E–I, white arrows) as shown in a 50-year-old female patient (E), a 67-year-old male patient (F, same patient as in Fig 2), a 55-year-old male patient (G and H, same patient as in Fig 1), and a 62-year-old female patient (I) with malignant melanoma. False-positive findings (turquoise) were related to blood vessels (E, developmental venous anomaly), variations in brain tissue contrast (F and G), and the choroid plexus (H and I).