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. Author manuscript; available in PMC: 2021 Apr 12.
Published in final edited form as: J Immunol. 2019 Nov 18;203(12):3237–3246. doi: 10.4049/jimmunol.1900245

Figure 2: Nrp1+Foxp3− CD4 T cells are more proliferative and highly activated cells.

Figure 2:

Chow and WD-fed ApoE−/− mice were injected with BrdU and CD4 T cells from the PaLN and aorta were harvested after 36 hours to detect the level of BrdU incorporation. (A) Flow cytometry plots and bar graphs showing the percentage of BrdU incorporated in Nrp1+Foxp3− versus Nrp1−Foxp3− CD4 T cells. (B) Histograms and bar graphs showing the expression of CD44 on Nrp1+Foxp3− versus Nrp1−Foxp3− CD4 T cells. Results are expressed as the mean ± s.e.m from one of two independent experiments (n=3). Statistically significant differences were at * P<0.05, ** P < 0.01, and *** P < 0.001.