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. Author manuscript; available in PMC: 2021 Apr 12.
Published in final edited form as: Clin Trials. 2020 Dec 1;18(1):3–16. doi: 10.1177/1740774520969136

Table 3:

Data modification for study i with zero events (i.e., either yi1 or yi2 is zero) using a constant 0.5

No. of events No. of nonevents Total

Control group yi1 + 0.5 ni1yi1 + 0.5 ni1 + 1
Treated group yi2 + 0.5 ni2yi2 + 0.5 ni2 + 1

Total yi· + 1 ni·yi· + 1 ni· + 2