Skip to main content
. 2020 Nov 29;23(4):599–610. doi: 10.1093/neuonc/noaa264

Figure 5.

Figure 5.

Effects of SERPINA3 KD in vivo. (A) Mice injected intracranially with 1A SERPINA3 KD cells survived longer than the control groups. (B) SERPINA3 KD groups showed decreased Ki67 proliferation index and (C) invasive capacity than the controls. (D) In vivo ELDA analysis showing lower tumor formation capacity in SERPINA3 KD BTICs than the controls. (E, F) ELDA in vivo tumors in the SERPINA3 KD group weighed less and had a decreased Ki67 proliferation index than the controls. *P < .05, **P < .01. Scale 2 mm and 200 µm. BTIC, brain tumor-initiating cell; ELDA, extreme limiting dilution assay; KD, knockdown.