Figure 3.

The loss of cat-1/VMAT protein results in altered monoaminergic behaviors. A, The grazing response is deficient in the cat-1 (ok411) mutant strain and N2 worms treated with reserpine (n = 1289). B, cat-1 (ok411) worms and N2 worms treated with reserpine have impaired pharyngeal pumping compared with N2 (n = 89). C, cat-1 (ok411) and N2 worms treated with reserpine are deficient in egg laying (more eggs in utero) (n = 114). D, There is no difference in wave initiation between N2 and the cat-1 (ok411) mutant (n = 55). N2_res = N2 worms treated with reserpine. All behaviors analyzed using 1-way ANOVA followed by Tukey’s multiple comparisons tests where appropriate. ** p < .01, *** p < .001 vs. all other groups, **** p < .0001 vs. all other groups.