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. 2021 Jan 22;180(2):239–251. doi: 10.1093/toxsci/kfab005

Figure 6.

Figure 6.

Induction of AHR-driven genes in heterozygous truncated mutants (Ahrb1/Ter383) compared with homozygous wild-type (Ahrb1/b1) and haploinsufficient (Ahrb1/-) controls. Mice are treated with βNF or corn oil vehicle control (CO) for 4 h. Liver mRNA expression of AHR-driven genes relative to Hprt. Groups sharing a superscript are not different at the level of statistical significance (p > .05) determined by a 2-way ANOVA with multiple comparisons of the means (Tukey’s multiple comparison test). Each point represents the mean of 3 technical replicates of 1 biological replicate. Males are represented by a circle whereas females are represented by a square. Error bars represent standard error of the mean.